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Artificial Life: Here It Comes

mycoplasmagenitalium.jpg

Last week The Guardian reported that Dr. J. Craig Venter, founder of The Institute for Genomic Research, will soon announce that his team of scientists has created the first artificial organism made from synthetic chromosomes. This will mark the first time that a synthetic life form has been created in a lab. The chromosome for the new species of bacteria is 381 genes long and contains 580,000 base pairs of genetic code. The basis of the organism comes from the bacterium called Mycoplasma genitalium. Venter's team removed one-fifth of the Mycoplasma genitalium's genetic material and replaced it with their synthetic chromosome. Then they transplanted the genetic material into a living bacteria, anticipating that this process will create a new species. This species, most likely to be named Mycoplasma laboratorium, is being patented by Dr. Venter.

The project opens up a number of questions regarding “designer genomes” and the potential advantages and risks of manipulating DNA with synthetic chemicals. Venter has stated that possible uses for synthetic species include new types of medical treatments, alternative energy sources, and, most frighteningly, new forms of biological weapons. Several philosophical and ethical questions are raised by the project, including the ethics of creating and patenting new species of biological life, and the authority of science to introduce new organisms into our planetary ecology without an adequate knowledge of possible environmental consequences.

Dr. Venter has been notorious for stirring up controversy, attempting to commercialize and patent the genome project, and exhibiting a penchant for sensationalistic self-publicizing. There have already been some critical responses to the Mycoplasma laboratorium project in the media and the blogosphere, such as Dr. Nick Gay's editorial response in The Guardian, claiming that Venter's project is a clever sham that does not actually advance scientific research.

Venter, for his part, seems intent on ignoring criticism of the project, boldly stating in the Guardian article, "We are not afraid to take on things that are important just because they stimulate thinking,' he said. 'We are dealing in big ideas. We are trying to create a new value system for life. When dealing at this scale, you can't expect everybody to be happy."

 

Tristan Gulliford is a writer, dreamer, and aspiring myth-keeper who makes electronic music under the name "Dreamcode". He is currently attending the University of Colorado at Boulder.

Comments

I think it is interesting

I think it is interesting how, in the "academic" world so many jump at the change to criticize new ideas, ("claiming that Venter's project is a clever sham that does not actually advance scientific research"). I believe this cynicism sprouts from fear and must commend Dr. Venture for taking on the difficult task of ignoring his critics; being in law school I understand how hard that is.--This is some pretty interesting stuff!

Well, at Least You Made me Laugh!

Why? "Artificial Life: Here It Comes" No it doesn't. Venter isn't creating life. This is completely absurd. Injecting an artificially created organic compound into an existing organism is exactly what Dr. Gay says it is. This is the most obvious dead end masquerading as something "cool" I've seen in a long time.

Humans will never, ever "create life" except the way they always have. Organisms are not machines. :-) Jesus, this is like going back 300 years! -- and it's exactly opposite to the kind of holistic, integrated mind/body awareness that's leading humanity to the next stage.

Is Venter full of hot air?

My understanding is that Venter's claim is that the injection of an artificial chromosome into an existing organism fundamentally changes its genetic makeup and constitutes the creation of a new lifeform. Of course, this is debatable.... which is why I included Nick Gay's response as part of this article. Regardless of the whether Venter's claim of creating new life is tenable, he is in fact publicly making the claim.

 

However, I think the larger and more interesting debate is the legality and ethics of manipulating living organisms without fully taking into account their possible effect on the biological ecosystem.

Hmmm

yeah untill it forms into a human and kills us all and ends the world....just a thought